The English Angora travels safest in a secure, well-ventilated carrier with non-slip, familiar bedding, ideally seatbelted so it cannot slide during the journey. Loose rabbits in a moving vehicle are at serious risk of injury.
Heat is the foremost danger. A heavily wooled breed overheats easily, so the cabin must be kept cool, the carrier kept out of direct sun, and the rabbit never left alone in a parked car, where temperatures rise to lethal levels within minutes. For longer trips in warm weather, cooling aids such as cloth-wrapped frozen bottles can help.
Offer familiar hay and water, minimize handling and noise, and plan calm stops to check the animal. Many rabbits refuse food when stressed; since prolonged loss of appetite is a medical emergency in rabbits, monitor eating closely after arrival.