Health

Health concerns within the breed include hip and elbow dysplasia, progressive retinal atrophy, bloat, and cancer, with a relatively high incidence of lymphoma and mast cell tumours. Bullmastiffs are prone to certain hereditary diseases, including:

Hip dysplasia, affecting 24.5% of individuals

Elbow dysplasia, affecting 13.8% of individuals

Entropion, hypothyroidism affecting 2.8% of individuals

Lymphoma

Progressive retinal atrophy is a particular problem, since the trait is an autosomal dominant one. (This has recently been called into question by another medical team and has been proven that some Bullmastiffs have autosomal recessive PRA genes. In America, this is being investigated by the American Bullmastiff Health and Research Committee, and the DNA Optigen test only works for dominant genes, so it is considered inadequate at this time.)

Health

While larger breeds of canines tend to have shorter life expectancy, the life expectancy of the Dogue is still shorter than even breeds of comparable or larger size. According to data collected by the Dogue De Bordeaux Society of America, the average lifespan of the breed is 5 to 6 years. A veterinary database in the UK showed similar figures. In the American survey, the oldest dog in the record was 12 years old. However, the acting dog who played Hooch in the 1989 film, Turner and Hooch, died at the age of 14. The Society is actively recording dogs that are 7 years old or older to celebrate the longer-lived dogs.

Because of its brachycephalic head, the Dogue can be affected by breathing problems. Some may be intolerant of heat or exercise as a result. The brachycephalic head shape can also encourage ectropion—an outward rolling of the lower eyelid which can lead to conjunctivitis (eye inflammation) and bacterial infections. Under the UK Kennel Club's Breed Watch system, the Dogue is classed as a Category 3 breed (formerly High Profile Breed), meaning it is a breed "where some dogs have visible conditions or exaggerations that can cause pain or discomfort."

Aortic stenosis is a disease of the heart valve in which the opening of the aortic valve is narrowed. Symptoms include exercise intolerance, exertional syncope (fainting from physical exertion) and sudden death. One study suggests a high predisposition in the breed. No severe cases were found in adult dogs, and most moderate to severely affected dogs died before one year of age, leading the authors to speculate that the disease is more severe in the Dogue than in other breeds.

Another heart problem in the breed is dilated cardiomyopathy, a condition in which the heart becomes weakened and enlarged and cannot pump blood efficiently. Some affected dogs may die suddenly without showing any signs of problems. Others may die from congestive heart failure after several weeks or months. Affected dogs are often euthanized at an early stage to avoid suffering.

An estimated 5% of dogs may be affected by footpad hyperkeratosis, a thickening of the footpad and sometimes nose. Lesions usually occur at the age of 6 months. X-rays submitted voluntarily to the Orthopedic Foundation for Animals shows that more than 50% of Dogues in the database are affected by hip dysplasia. Over 21% are affected by elbow dysplasia. Approximately 3% of Dogues suffer from retinal dysplasia. Patella luxation affects around 2% of Dogues.