The Neo is the most commonly used affectionate nickname for the Neapolitan Mastiff, embraced by owners and enthusiasts worldwide who appreciate the breed's gentle nature despite their fearsome appearance. This shortened designation reflects the close bond between these massive dogs and their families, making the formal breed name more manageable in everyday conversation. The nickname "Neo" has become so widely accepted that it appears regularly in breed literature, online forums, and casual discussions among Mastiff lovers.
Historically, the breed has been known by several Italian names reflecting its Naples heritage, including "Mastino Napoletano" which remains the official designation in Italy, and simply "Mastino" among Italian breeders and fanciers. In southern Italy where the breed developed, these dogs were often called "the big dog of the little man," referencing their role as protectors for ordinary families and small landowners who relied on the breed's imposing presence to guard homes and property. This democratic association distinguished the Neo from more aristocratic mastiff breeds that served nobility.
The designation "Italian Mastiff" also appears in breed documentation and historical references, emphasizing the breed's distinct Italian heritage and separating it from other mastiff varieties developed in different countries. This name helps clarify that while sharing the mastiff designation with breeds from England, Spain, and elsewhere, the Neo possesses unique characteristics shaped by centuries of selective breeding in southern Italy. The Italian Mastiff name appears frequently in early 20th century breed registration documents.
International kennel organizations recognize the breed under its formal Neapolitan Mastiff designation, though the pathway to official recognition came relatively late in the breed's long history. The Ente Nazionale della Cinofilia Italiana, Italy's national kennel club, granted initial recognition in 1949 following the work of journalist Piero Scanziani who discovered the breed at a Naples dog show in 1946. His efforts to document and standardize the breed resulted in the first official breed standard written in 1948.
The Federation Cynologique Internationale extended full international recognition in 1956, classifying the Neo in Group 2 for Pinscher and Schnauzer types, Molossoid breeds, Swiss Mountain and Cattle Dogs. This FCI recognition established breed standards followed by member countries across Europe, Asia, and South America. The American Kennel Club granted recognition much later in 2004, placing the breed in the Working Group. The United Kennel Club recognized the breed in 1995, also in the Working Group, while The Kennel Club in the United Kingdom includes the Neo in the Working Group classification as well. This international recognition ensures breed standards maintain the Neo's essential characteristics across different regions and breeding programs.

