The Cinses Hairless Dog is generally a healthy breed with a notable lifespan of 13 to 18 years, placing it among the longer-lived toy breeds. However, several conditions occur at elevated rates and deserve informed attention from owners and breeders. The most significant health concerns cluster around three areas: eye diseases, orthopedic conditions, and the skin and dental issues directly linked to the hairlessness gene. Understanding these vulnerabilities enables effective preventive care, early detection, and responsible breeding decisions that benefit individual dogs and the breed population as a whole.
Eye diseases represent the most consequential inherited health challenge. Primary lens luxation, caused by an autosomal recessive mutation of the ADAMTS17 gene, occurs at higher rates in the Chinese Crested than in most other breeds. The fibers holding the lens in position degenerate, allowing the lens to shift forward or backward within the eye. The condition is painful, progresses rapidly, and can lead to secondary glaucoma and blindness without prompt surgical intervention. Progressive retinal atrophy, present in at least two genetically distinct forms, causes slow, irreversible degeneration of the retinal photoreceptor cells and eventual blindness. DNA tests exist for PLL and for one form of PRA (prcd-PRA), enabling breeders to identify carriers. However, because the available DNA tests do not cover all PRA forms in the breed, annual ophthalmologic examinations by a board-certified veterinary ophthalmologist remain essential regardless of genetic test results. Keratoconjunctivitis sicca, or dry eye, also occurs at notable frequency.
Orthopedic conditions common in the breed include patellar luxation and Legg-Calve-Perthes disease, both disproportionately affecting toy breeds. Patellar luxation involves displacement of the kneecap from its normal groove, producing intermittent limping, a skipping gait, or chronic lameness depending on the severity grade. Legg-Calve-Perthes disease causes avascular necrosis of the femoral head, typically appearing between five and eight months of age with signs of progressive hind-limb lameness and muscle wasting. Both conditions can be screened through veterinary examination, and both may require surgical correction in moderate to severe cases.
Dental abnormalities in the Hairless variety deserve particular attention because they are genetically linked to the hairlessness trait itself. The incomplete dominant gene that produces the Hairless phenotype also affects tooth development, resulting in fewer teeth, abnormally shaped teeth, and early tooth loss. Many Hairless individuals lose a significant portion of their dentition by age two or three. This outcome is a genetic inevitability rather than a consequence of poor care, though daily dental maintenance starting in puppyhood can slow the progression of periodontal disease. Dietary adjustments such as softened food may become necessary as teeth are lost. The Powderpuff variety has normal toy breed dentition but remains susceptible to the periodontal disease common in small dogs.
Additional health concerns include congenital deafness confirmable through BAER testing, various skin conditions in the Hairless variety including acne, comedones, sunburn, and allergic dermatitis, and occasional occurrences of hypothyroidism and idiopathic epilepsy. Responsible breeders use available health screening tools, including the CHIC-required eye, patella, and cardiac evaluations along with optional DNA tests for PLL and PRA and BAER testing, to minimize transmission of inherited conditions.
Common Health Issues
- Primary lens luxation (PLL) - An inherited eye condition caused by an autosomal recessive mutation of the ADAMTS17 gene that causes the lens support fibers to degenerate, allowing the lens to dislocate. The breed has a higher incidence of PLL than most others. The condition is painful, develops rapidly, and can lead to blindness and secondary glaucoma. A DNA test identifies clear, carrier, and affected dogs.
- Progressive retinal atrophy (PRA) - A group of inherited diseases causing gradual degeneration of the retinal photoreceptor cells, leading to progressive vision loss and eventual blindness. At least two forms affect the breed. A DNA test exists for one form (prcd-PRA), but regular ophthalmologic examinations remain necessary because the test does not cover all forms present in the breed.
- Patellar luxation - A common orthopedic condition in toy breeds where the kneecap slips from its normal groove, causing intermittent lameness, skipping gait, or chronic pain depending on severity. Grading ranges from I (mild, occasional slipping) to IV (permanent dislocation with skeletal changes). Moderate to severe cases may require surgical correction.
- Legg-Calve-Perthes disease - Avascular necrosis of the femoral head in which reduced blood supply causes the top of the thighbone to deteriorate, producing hip pain, limping, and muscle wasting. The condition typically appears between five and eight months of age. Surgical removal of the damaged femoral head generally yields good functional outcomes in small breeds.
- Dental disease and tooth abnormalities - The Hairless variety has a genetic link between the hairlessness gene and dental development, resulting in fewer teeth, peg-shaped or forward-sloping teeth, and early tooth loss. Many Hairless individuals lose significant numbers of teeth by age two or three. The Powderpuff variety has normal toy breed dentition but remains susceptible to periodontal disease.
- Keratoconjunctivitis sicca (dry eye) - Insufficient tear production leaving the corneal surface inadequately lubricated, causing irritation, redness, mucoid discharge, and potential corneal ulceration. Requires lifelong management with topical immunosuppressive medications to stimulate tear production and artificial tear supplements.
- Congenital deafness - Some puppies are born with partial or complete hearing loss confirmed through brainstem auditory evoked response (BAER) testing. Deaf dogs can live full lives with hand-signal training and vibration-based cues. Breeders should BAER test their stock to make informed breeding decisions.
- Skin conditions (Hairless variety) - The exposed skin of the Hairless variety is susceptible to acne, blackheads, sunburn, dry skin, and allergic reactions. Regular bathing, appropriate moisturizing, and sun protection are essential. Some individuals develop contact allergies to fabrics, detergents, or grooming products.
Preventive Care & Health Monitoring
- CERF or OFA CAER eye examination by a board-certified veterinary ophthalmologist - Required CHIC test. Annual examinations detect early signs of PRA, PLL, dry eye, and other ocular conditions. Critical given the breed's elevated risk for multiple eye diseases.
- OFA patellar luxation evaluation - Required CHIC test. Veterinary examination of knee joint stability with results registered with OFA. Recommended for all dogs to catch early-stage luxation before clinical lameness develops.
- OFA cardiac evaluation - Required CHIC test. Auscultation by a veterinarian or board-certified cardiologist to screen for congenital heart defects, with results registered with OFA.
- DNA test for primary lens luxation (PLL) - Optional CHIC test but strongly recommended. Identifies clear, carrier, and affected dogs for the ADAMTS17 gene mutation. Essential for informed breeding decisions given the breed's elevated PLL risk.
- DNA test for progressive retinal atrophy (prcd-PRA) - Optional CHIC test but strongly recommended. Identifies genetic status for one form of PRA. Should be used alongside regular ophthalmologic examinations rather than as a standalone screening tool.
- BAER hearing test - Optional CHIC test. Brainstem auditory evoked response testing confirms hearing status in puppies and breeding dogs, helping breeders identify carriers of congenital deafness.
- Daily dental care and professional dental cleanings - Daily tooth brushing is essential given the breed's high susceptibility to dental disease, especially in the Hairless variety. Professional veterinary dental cleanings should be scheduled annually or more frequently for dogs with abnormal dentition.
- Sun protection for Hairless variety - Apply pet-safe sunscreen to exposed skin before outdoor activity and limit direct sun exposure during peak hours. Lightweight protective clothing provides additional coverage during extended outdoor time.