The Multimammate Mouse has an extensive presence in the peer-reviewed scientific literature, though this body of work addresses the species primarily as a research subject rather than as an animal of intrinsic popular interest. Thousands of published papers reference Mastomys natalensis or its congeners, spanning disciplines from virology and parasitology to ecology, reproductive biology, and agricultural science. The sheer volume of this literature reflects the species' outsized importance in multiple fields of inquiry, and its citation record rivals that of far more widely known rodent species in certain specialized domains.
The earliest significant wave of scientific publications concerning Mastomys emerged in the 1970s, driven by the identification of the species as the natural reservoir of Lassa virus. Papers published in journals such as the Bulletin of the World Health Organization, the American Journal of Tropical Medicine and Hygiene, and the Lancet established the epidemiological link between Mastomys populations and Lassa fever outbreaks in West Africa. These foundational studies were widely cited and introduced the species to a broad audience of infectious disease researchers who might otherwise have had little reason to encounter an obscure African murid rodent in their work.
A second major current in the scientific literature centers on the use of Mastomys as a model organism in cancer research. Publications from the 1980s and 1990s described the natural occurrence of gastric carcinoid tumors in laboratory colonies of Mastomys coucha, generating a body of oncology literature that treated the species as a unique and valuable tool for understanding gastric neoplasia. These papers appeared in high-impact journals including Cancer Research, Gastroenterology, and the Journal of the National Cancer Institute, lending the species a degree of scientific prestige that few other exotic rodents enjoy.
More recent publications have expanded the scientific profile of Mastomys into the domains of ecology, population genetics, and conservation biology. Studies examining the species' population dynamics in agricultural landscapes, its role in seed dispersal and vegetation dynamics, and its genetic structure across its vast geographic range have appeared in journals such as the Journal of Mammalogy, Molecular Ecology, and the African Journal of Ecology. This ecological literature has added depth and nuance to the scientific understanding of a species that was previously known almost exclusively through the lens of its medical and agricultural significance.