Cars are the most realistic way to travel with a Mini Lop, and most rabbits tolerate short trips reasonably well in a secure carrier. The carrier should be hard-sided or sturdily framed, well ventilated, and anchored with a seatbelt so it cannot slide or tip.
Temperature is the single biggest risk. Rabbits are highly sensitive to heat and can suffer fatal heatstroke in a warm car far faster than people expect, so a parked vehicle should never be used as a holding space and air conditioning should be running in warm weather.
Stress management rounds out the basics. Lining the carrier with familiar bedding, offering hay and a water source for longer trips, keeping the cabin quiet, and minimizing total travel time all help reduce the digestive upset that stress can trigger in rabbits.