Bacterial Infections
Brucellosis is a sexually transmitted bacterial disease that can cause uveitis, abortion, and orchitis in dogs.
Leptospirosis is an infectious disease caused by a spirochaete. Symptoms include liver and kidney failure and vasculitis.
Lyme Disease is a disease caused by Borrelia burgdorferi, a spirochaete, and spread by ticks of the genus Ixodes. Symptoms in dogs include acute arthritis, anorexia, and
lethargy. There is no rash as is typically seen in humans.
Ehrlichiosis is a disease caused by Ehrlichia canis and spread by the brown dog tick, Rhipicephalus sanguineous. Signs include fever, vasculitis, and low blood counts.
Rocky Mountain Spotted Fever is a rickettsial disease that occurs in dogs and humans. It is caused by Rickettsia rickettsii and spread by ticks of the genus Dermacentor.
Signs are similar to human disease, including anorexia, fever, and thrombocytopenia.
Clostridium species are a potential cause of diarrhea in dogs. Associated species include C. perfringens and C. difficile.
Kennel Cough is an infectious respiratory disease which can be caused by one of several viruses or by Bordetella bronchiseptica. It most commonly occurs in dogs in close
confinement such as kennels.
Fungal Infections
Blastomycosis is a fungal disease caused by Blastomyces dermatitidis that affects both dogs and humans. Dogs are ten times more likely to be infected than humans. The
disease in dogs can affect the eyes, brain, lungs, skin, or bones.
Histoplasmosis is a fungal disease caused by Histoplasma capsulatum that affects both dogs and humans. The disease in dogs usually affects the lungs and small
intestine.
Coccidioidomycosis is a fungal disease caused by Coccidioides immitis that affects both dogs and humans. In dogs signs include coughing, fever, lethargy, and
anorexia. Many cases include lameness due to bome lesions.
Cryptococcosis is a fungal disease caused by Cryptococcus neoformans that affects both dogs and humans. It is a rare disease in dogs, with cats seven to ten times
more likely to be infected. The disease in dogs can affect the lungs and skin, but more commonly the eye and central nervous system.
Ringworm is a fungal skin disease that in dogs is caused by Microsporum canis (70%), Microsporum gypseum (20%), and Trichophyton mentagrophytes (10%). Typical signs
in dogs include hair loss and scaly skin.
Sporotrichosis is a fungal disease caused by Sporothrix schenckii that affects both dogs and humans. It is a rare disease in dogs, with cat and horse infections
predominating in veterinary medicine. The disease in dogs is usually nodular skin lesions of the head and trunk.
Aspergillosis is a fungal disease that in dogs is caused primarily by Aspergillus fumigatus. Infection is usually in the nasal cavity. Typical signs in dogs include
sneezing, nasal discharge, bleeding from the nose, and ulcerations of the nose.
Pythiosis is a disease cause by a water mould of the genus Pythium, P. insidiosum. It occurs primarily in dogs and horses, but can also affect humans. In dogs it
affects the gastrointestinal system and lymph nodes, and rarely the skin.
Mucormycosis is a collection of fungal and mold diseases in dogs including pythiosis, zygomycosis, and lagenidiosis that affect the gastrointestinal tract and skin.
Protozoal diseases
Giardiasis is an intestinal infection in dogs caused by the protozoa Giardia lamblia. The most common symptom is diarrhea. The zoonotic potential of
giardiasis is controversial.
Coccidiosis can be caused by a variety of coccidian organisms in dogs, most commonly Isospora. There are usually no symptoms, but diarrhea and weight loss
may occur.
Leishmaniasis is spread by the sandfly, and in the dog as well as human has both cutaneous and visceral forms. The dog is considered to be the reservoir for
human disease in the Americas.
Babesiosis is spread by members of the family Ixodidae, or hard ticks. The two species of the genus Babesia that affect dogs are B. canis and B. gibsoni.
Babesiosis can cause hemolytic anemia in dogs.
Neosporosis is caused by Neospora caninum
Other infections
Protothecosis in dogs is caused by a mutant form of green algae and is usually disseminated. Symptoms include weight loss, uveitis, and retinal detachment.
Parasites
Intestinal parasites
Hookworms are a common parasite of dogs. Most common is Ancylostoma caninum, followed by Uncinaria stenocephala and A. braziliense. Signs include
diarrhea, vomiting, and weight loss.
Tapeworms are also common and in the dog are usually Dipylidium caninum, which is spread by ingesting fleas and lice. Also common is Taenia pisiformis, spread
by ingesting rabbits and rodents. Rare tapeworm infections are caused by species of the genera Echinococcus, Mesocestoides, and Spirometra. There are usually no
symptoms.
Roundworms infecting the dog include Toxocara canis and Toxascaris leonina. Signs are usually mild, but may include diarrhea,
pot-bellied appearance, poor growth, and vomiting.
Fleas in dogs cause itching and hair loss. The most common flea in dogs is the cat flea, Ctenocephalides felis, followed by the dog flea, C. canis.
Ticks are an external parasite of the dog and can spread diseases such as Lyme disease, Rocky Mountain spotted fever, babesiosis, and ehrlichiosis. They can
also cause a neurological disorder known as tick paralysis.
Heartworm disease in dogs is spread by mosquitoes and is spread by the parasite Dirofilaria immitis. Signs include cough, difficulty breathing, and death.
Mites
Ear mites in dogs are microscopic members of the species Otodectes cynotis. Symptoms include itching, inflammation, and black debris in the ear.
Cheyletiellosis is a mild pruritic skin disease in dogs caused by Cheyletiella yasguri. Humans can be transiently infected.
Chiggers can cause itching, redness and crusting in dogs.
Demodectic Mange is caused by Demodex canis. Signs include hair loss, redness, and scaling,
and is not contagious to humans.
Sarcoptic Mange is caused by Sarcoptes scabiei canis. Signs include intense itching and scaling, and is contagious to humans.
Skeletal and muscular disorders
Osteoarthritis, also known as degenerative arthritis, is a common condition in dogs characterized by progressive deterioration of articular cartilage in the
joints of the limbs. It can cause a great deal of pain and lameness. Treatment options include medications such as NSAIDs, corticosteroids, and joint fluid modifiers
such as glycosaminoglycans. Other treatments include surgery, massage, warm compresses, chiropractic, and acupuncture.
Hip Dysplasia is an inherited disease in dogs that is characterized by abnormal development of the acetabulum and head of the femur. It is more common in
large breeds.
Elbow Dysplasia is a condition found more commonly in large breeds. It incorporates several different hereditary conditions of the elbow, including
osteochondritis of the medial condyle of the humerus, fragmentation of the medial coronoid process of the ulna, and ununited anconeal process of the ulna.
Luxating Patella is a medial or lateral displacement of the patella, or kneecap. It is strongly suspected to be inherited, but can also result from trauma.
It is more common in smaller breeds of dogs.
Osteochondritis Dissecans (OCD) is separation of immature articular cartilage from underlying bone. It is caused by osteochondrosis, which is characterized by
abnormal endochondral ossification of epiphyseal cartilage. It is most commonly seen in the stifle, elbow, shoulder, and hock.
Panosteitis is a common disease of unknown cause that causes pain and a shifting leg lameness in medium and large breed dogs. It affects the long bones of the hind
and forelimbs.
Legg-Calvé-Perthes Syndrome also known as Perthes disease or aseptic necrosis of the femoral head, is characterized by a deformity of the head of the femur and hip
pain. It occurs in small breed puppies.
Back Pain in dogs, particularly in long-backed breeds, such as Basset Hounds and Dachshunds, is usually caused by
intervertebral disk disease. It is caused by
degeneration and protrusion of the disk and compression of the spinal cord. It occurs most commonly in the cervical and thoracolumbar regions. Signs include back pain, hind
limb weakness, and paralysis.
Congenital Vertebral Anomalies including butterfly, block, and transitional vertebrae, and hemivertebrae, are a collection of malformations of the spine in animals.
Most are not clinically significant, but they can cause compression of the spinal cord by deforming the vertebral canal or causing instability.
Craniomandibular Osteopathy is a hereditary disease in West Highland White Terriers and also occurs in other terrier breeds. It is a developmental disease in puppies
causing extensive bony changes in the mandible and skull. Signs include pain upon opening the mouth.
Hypertrophic Osteopathy is a bone disease secondary to disease in the lungs. It is characterized by new bone formation on the outside of the long bones.
Hypertrophic Osteodystrophy is a bone disease in rapidly growing large breed dogs. Signs include swelling of the metaphysis (the part of the bone adjacent to the
joint), pain, depression, loss of appetite, and fever. The disease is usually bilateral in the limb bones.
Spondylosis, known as spondylosis deformans in dogs, is growth of osteophytes on the ventral and lateral surfaces of the vertebral bodies. It is usually an incidental
finding on radiographs and rarely causes symptoms.
Masticatory Muscle Myositis (MMM) is an inflammatory disease in dogs affecting the muscles of the jaw. Signs include swelling of the jaw muscles and pain on opening
the mouth. In chronic MMM there is atrophy of the jaw muscles, and scarring of the masticatory muscles due to fibrosis may result in inability to open the mouth (trismus).
Cardiovascular and circulatory
Platelet disorders
von Willebrand Disease is an inherited, common disease found in both dogs and humans. It is characterized by a deficiency of a protein called von Willebrand
factor, which is involved in blood clotting. The disease varies from mild to severe, depending on the amount of von Willebrand factor present in the dog. Signs
include spontaneous bleeding and excessive bleeding following surgery, injury, or during an estrous cycle.
Thrombocytopenia is a common condition in dogs characterized by low platelet counts. Platelets are used in clotting the blood, so dogs with this condition may
have spontaneous bleeding or prolonged bleeding following surgery, injury, or during an estrous cycle. Causes include some rickettsial infections such as
ehrlichiosis, cancers such as hemangiosarcoma, or immune-mediated disease.
Thrombocytosis is a condition characterized by an excess of platelets. Most cases are physiologic (caused by exercise) or reactive (secondary to some cancers,
blood loss, or certain drugs). Rarely the condition is caused by a primary bone marrow disorder. In this last case, the platelets may not function normally, causing
the blood to not clot properly.
Hemolytic Anemia is a type of regenerative anemia found in dogs characterized by destruction of the red blood cell. The most important type is immune-mediated
hemolytic anemia, which can be a primary disease or secondary to cancer, infection, drugs, or vaccinations. Antibodies are present on the cell surface, leading to
lysis and severe anemia. Other causes of hemolytic lesion include hypophosphatemia, exposure to toxins such as lead, infections such as ehrlichiosis or babesiosis,
and rarely, neonatal isoerythrolysis. The behavioral condition pica, especially when involving the eating of concrete dust, tile grout, or sand, may be a sign of
hemolytic anemia, indicating the need for a complete blood count to investigate a possible diagnosis.
Heart Diseases
Degenerative Mitral Valve Disease is a common cause of congestive heart failure in dogs, especially small, older dogs. The leaflets of the valve become
thickened and nodular, leading to mitral valve regurgitation and volume overload of the left side of the heart. Cavalier King Charles Spaniels have an inherited form
of this disease.
Dilated Cardiomyopathy is a disease of heart muscle resulting in atrial and ventricular dilation. It is seen in large dog breeds such as Boxers, Great Danes,
and Dobermanns. It is usually idiopathic, but can also be caused by taurine deficiency in Cocker Spaniels or doxorubicin use. Dilated cardiomyopathy usually results
in congestive heart failure.
Congestive Heart Failure is any heart disease that results in the inability to put out enough blood to meet the dog's needs. It can be caused by the above two
diseases, heat stroke, electric shock, injury, infection, developmental heart defects, or high blood pressure. Signs depend on which side of the heart is affected.
Left-sided heart failure may result in coughing and difficulty breathing from a build-up of fluid in the lungs (pulmonary edema) and fainting. Right-sided heart
failure may result in a build-up of fluid in the abdomen (ascites), fluid around the lungs (pleural effusion), or peripheral edema.
Sick Sinus Syndrome is most commonly seen in female Miniature Schnauzers. It is characterized by sinoatrial node dysfunction and often includes
atrioventricular node disease and bundle branch block. Electrocardiogram findings include sinus bradycardia, sinus arrest, sinoatrial heart block, and asystole. The
major sign is fainting.
Various heart defects
Aortic Stenosis is a congenital disease in dogs characterized by left ventricular outflow tract obstruction. It is inherited in Newfoundlands, and also found
in Golden Retrievers, Rottweilers, Boxers, Bulldogs, German Shepherd Dogs, and Samoyeds. Signs include fainting and exercise intolerance.
Pulmonic Stenosis is a congenital disease in dogs characterized by right ventricular outflow tract obstruction. Most commonly the narrowing occurs at the
pulmonary valve. The most commonly affected breeds include terriers, Bulldogs, Miniature Schnauzers, Chihuahuas, Samoyeds, Beagles, Keeshonds, Mastiffs, and
Bullmastiffs. Signs include exercise intolerance, but often there is only a heart murmur.
Ventricular Septal Defect is a hole in the division between the heart ventricles. It is a congenital disease in dogs. There usually are no signs in dogs
except for a heart murmur.
Atrial Septal Defect is a hole in the division between the heart atria. It is an uncommon condition in dogs. Most are not clinically significant, but large
defects may cause heart failure, cyanosis, and exercise intolerance.
Tetralogy of Fallot is a congenital heart defect in dogs that includes four separate defects: pulmonic stenosis, a ventricular septal defect, right
ventricular hypertrophy, and an overriding aorta. Keeshonds and Bulldogs are predisposed. Signs include cyanosis and exercise intolerance.
Patent Ductus Arteriosus is the most common congenital heart defect in dogs in the United States. It is inherited in toy and miniature Poodles, and seen
commonly in Pomeranians, Bichon Frises, and Malteses. Signs include cough and exercise intolerance.
Heart Valve Dysplasia (including
mitral and
tricuspid valve dysplasia) is a congenital heart defect in dogs. Dysplasia of the mitral and tricuspid valves -
also known as the atrioventricular (AV) valves - can appear as thickened, shortened, or notched valves.
Cor Triatriatum, specifically cor triatriatum dexter, occurs in dogs and is characterized by a fibrous division of the right atrium. It can be treated by
balloon valvuloplasty.
Pericardial Effusion is a collection of fluid in the pericardium. It is usually serous (clear or yellow fluid) or serosanguinous (bloody fluid). Serious
accumulation is caused by heart failure, peritoneopericardial diaphragmatic hernias, uremia, pericardial cysts, or hypoalbuminemia. Serosanguinous accumulation can
be caused by cancer, usually hemangiosarcoma, idiopathic disease, trauma, clotting disorders, or left atrial rupture. Rarely pericardial effusion can be caused by
infection and consist of pus. Drainage of the fluid is the ideal treatment.
Pulmonary Hypertension is high pressure in the pulmonary artery. In dogs it can be caused by heartworm disease or pulmonary thromboembolism. It can result in
right-sided heart disease (cor pulmonale). Signs include difficulty breathing, cyanosis, and exercise intolerance.
Trapped Neutrophil Syndrome is an autosomal recessive disease which results in mature neutrophils being unable to migrate from the bone marrow into the blood.
Affected pups suffer from chronic infections and failure to thrive. Other symptoms can include stunted growth and a ferret like facial appearance. The disease is
common in Border collies.
Continue to Page 2 of Canine Diseases...
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